H4CBD: what are we talking about?
The Hydrogenated CBD or hexahydrocannabidiol, better known as H4CBD, is the result of a semi-synthetic modification of cannabidiol, obtained in the laboratory by addition of hydrogen atoms to the molecular structure of CBD.
Its origin? It dates back to the mid-20th century, a time marked by an interest in the pain-relieving properties of cannabis. Since its first synthesis in the 1940s, H4CBD has unfortunately fallen into obscurity thanks to THC and CBD, widely studied by scientists.
Chemically and functionally, H4CBD is very similar to cannabidiol, but there is one major difference. While CBD has a moderate interaction with the “CB 1” receptor of our endocannabinoid system, which explains its moderate effects, H4CBD binds specifically to this receptor with very high affinity. This is also what pushes some scientists to talk about effects “up to 100 times more intense”. This assertion is, for the moment, not yet supported by reliable data.
What are the potential virtues of H4CBD?
H4CBD acts on several physiological functions, including mood, sleep and immunity. The information that we are going to give you comes from consumer feedback and clinical observations, and not from rigorous scientific studies.
The impact of H4CBD on the nervous system and mood
Thanks to its anti-stress and anti-anxiety properties, H4CBD is likely to significantly improve mood and reduce symptoms related to anxiety. It would also stimulate cognitive functions and the ability to concentrate, like the CBD from which it comes.
The anti-inflammatory properties of H4CBD
The anti-inflammatory action of H4CBD is undoubtedly the property that most interests scientists looking for less aggressive substances on steroidal and non-steroidal anti-inflammatory drugs. Unlike CBD which acts preferentially on muscle and joint inflammation, H4CBD seems to soothe inflammation linked to the digestive system.
H4CBD against autoimmune diseases
H4CBD could modulate the immune system and attenuate inflammation associated with autoimmune pathologies such as multiple sclerosis, Crohn's disease and lupus. Studies must still be carried out to validate this suspected effect.
H4CBD against sleep disorders
Like all non-psychotropic cannabinoids, H4CBD acts on the nervous system to reduce stress and anxiety, but also to promote falling asleep and improve the quality of sleep. Warning: H4CBD induces a more intense state of relaxation than CBD. The border with sedation is not far.
Editor’s note The effects of H4CBD remain to be proven, and its side effects have not yet been controlled. The product arriving in France in the summer of 2023 has not yet been sufficiently studied. This is why 321CBD has chosen not to market products containing H4CBD. |
